Metformin Hydrochloride is the hydrochloride salt of the biguanide metformin with antihyperglycemic and potential antineoplastic activities. Metformin inhibits complex I (NADPH:ubiquinone oxidoreductase) of the mitochondrial respiratory chain, thereby increasing the cellular AMP to ATP ratio and leading to activation of AMP-activated protein kinase (AMPK) and regulating AMPK-mediated transcription of target genes. This eventually prevents hepatic gluconeogenesis, enhances insulin sensitivity and fatty acid oxidation and ultimately leads to a decrease in glucose levels. Metformin may exert antineoplastic effects through AMPK-mediated or AMPK-independent inhibition of mammalian target of rapamycin (mTOR), which is up-regulated in many cancer tissues. Furthermore, this agent also inhibits tumor cell migration and invasion by inhibiting matrix metalloproteinase-9 (MMP-9) expression which is mediated through the suppression of transcription activator protein-1 (AP-1) activation.
Wednesday, October 4, 2017
HIGH SECURITY DOORS
AND TOOLS MICRO DREMEL 8050
1.
2 PROOF OF CONCEPT New Hypertherm Powermax 65 Plasma Cutting System
Tuesday, October 3, 2017
Monday, October 2, 2017
Ufff...its a complex issue, the anti copy features. they might just place a fake tumbler on the key (Abloy is worldest company selling the locks for banking trucks) that's one part of the question; the other part of the question which is (in my opinion) more accuared, is the cutting system of the key, which is exclusiv...now there's only two companies selling this cutters...what am I talking about ??' I'm taking that cuts are made on two different radius. and 2. it has a 100% chances that if the combination is not accuared the lock blocks the discks, and it going futher after 90.º degrees turn
welcome back to war! I imagine all of us on this particulary high security business know about this amazing tool
SARGENT & GREENLEAF U11 Safe-4 Wheel Combination Lock Change Key-S&G-FREE POST!
http://www.ebay.com/itm/SARGENT-GREENLEAF-U11-Safe-4-Wheel-Combination-Lock-Change-Key-S-G-FREE-POST-/131837362490
hey guys....Moscow East side...lol...do you know what this (coming from Israel?) foil impressing spacer tool for our....favourite locks...ahahahah "Next thing you do is put the foil over a special blank that already has the profile of your target lock. The clever thing about this tool is that the ‘U shaped foil tube’ is wrapped around some sort of needle, and the foil can not be pushed in when entering the lock! Once the key is inserted, the needle is taken out from the back of the tool, and the pins are now resting on the foil. Because of the cuts in the foil, each pin will stand on it’s own ‘island’ of foil, and when it is pushed in will not disturb the neighboring pin"
Sunday, October 1, 2017
Ok, everybody! first rule (CIA techniques) 1. trow soap in water plastic bags under the police car wheels. 2 trow wet tissues to police windows cars, and air exits trucks,and their spray mounted towers on the trucks. 3 take a picture with a cop that joint the movement!!!!!! fuck if its fake, Use it!
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